As filed with the Securities and Exchange Commission on February 28, 2024

Registration No. 333-   






Washington, D.C. 20549










(Exact Name of Registrant as Specified in Its Charter)




The Netherlands   Not Applicable

(State or other jurisdiction of

incorporation or organization)


(I.R.S. Employer

Identification No.)

Uppsalalaan 17

3584 CT Utrecht

The Netherlands

(Address of Principal Executive Offices) (Zip Code)

Merus N.V. 2016 Incentive Award Plan

(Full Title of the Plan)

Sven (Bill) Ante Lundberg

c/o Merus US, Inc.

139 Main St. Suite 302

Cambridge, Massachusetts 02142

(Name and Address of Agent for Service)

+1 (617) 401-4499

(Telephone Number, including Area Code, of Agent for Service)



Copies to:


Peter N. Handrinos

Latham & Watkins LLP

200 Clarendon Street

Boston, MA 02116

(617) 948-6060


Paul van der Bijl

NautaDutilh N.V.

Beethovenstraat 400

1082 PR Amsterdam

The Netherlands

+31 20 717 1000



Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.


Large accelerated filer      Accelerated filer  
Non-accelerated filer      Smaller reporting company  
     Emerging growth company  

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐






This Registration Statement on Form S-8 is being filed for the purpose of registering an additional 9,534,386 common shares, nominal value €0.09 per share, of Merus N.V. (the “Registrant”) that may become issuable under the Merus N.V. 2016 Incentive Award Plan, as amended. A Registration Statement of the Registrant on Form S-8 relating to the same employee benefit plan is effective.



Except as set forth below, the contents of the Registration Statements on Form S-8 (File Nos. 333-211497, 333-230708 and 333-254345) filed with the Securities and Exchange Commission, relating to the 2016 Plan, are incorporated by reference herein.

Item 8. Exhibits.


   Description of Exhibit
4.1    Articles of Association of Merus N.V. (incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K (File. No. 001-37773) filed on May 28, 2021).
5.1+    Opinion of NautaDutilh N.V., counsel to the Registrant.
23.1+    Consent of KPMG Accountants N.V., independent registered public accounting firm.
23.2+    Consent of NautaDutilh N.V., counsel to the Registrant (included in Exhibit 5.1).
24.1+    Power of Attorney (included on signature page).
99.1    Merus N.V. 2016 Incentive Award Plan and forms of award agreements thereunder (incorporated by reference to Exhibit 4.2 to the Registrant’s Annual Report on Form 20-F (File. No. 001-37773) filed on April 30, 2018).
107.1+    Filing Fee Table



Filed herewith


Pursuant to the requirements of the Securities Act of 1933, as amended, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Newton, Massachusetts, on February 28, 2024.



/s/ Sven (Bill) Ante Lundberg


Sven (Bill) Ante Lundberg

President and Chief Executive Officer


Each of the undersigned officers and directors of the registrant hereby severally constitutes and appoints Sven A. Lundberg and Gregory D. Perry, and each of them singly (with full power to each of them to act alone), as his or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution in each of them, for him or her and in his or her name, place and stead, and in any and all capacities, to file and sign any and all amendments, including post-effective amendments, to this registration statement and any other registration statement for the same, with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith and about the premises as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or their substitute or substitutes, may lawfully do or cause to be done by virtue hereof. This power of attorney shall be governed by and construed with the laws of the State of Delaware and applicable federal securities laws.

Pursuant to the requirements of the Securities Act of 1933, as amended, this registration statement has been signed below by the following persons on behalf of the registrant in the capacities and on the dates indicated.







/s/ Sven (Bill) Ante Lundberg

Sven (Bill) Ante Lundberg

   President, Chief Executive Officer and Director (principal executive officer)    February 28, 2024

/s/ Gregory D. Perry

Gregory D. Perry


Chief Financial Officer

(principal financial officer)

   February 28, 2024

/s/ Harry Shuman

Harry Shuman


Chief Accounting Officer

(principal accounting officer)

   February 28, 2024

/s/ Anand Mehra

Anand Mehra

   Chairman of the Board of Directors    February 28, 2024

/s/ Maxine Gowen

Maxine Gowen

   Director    February 28, 2024

/s/ Mark T. Iwicki

Mark T. Iwicki

   Director    February 28, 2024

/s/ Len Kanavy

Len Kanavy

   Director    February 28, 2024

/s/ Paolo Pucci

Paolo Pucci

   Director    February 28, 2024

/s/ Victor Sandor

Victor Sandor

   Director    February 28, 2024


Pursuant to the Securities Act of 1933, as amended, the undersigned, the duly authorized representative in the United States of MERUS N.V. has signed this registration statement in the City of Newton, Massachusetts, the United States of America on February 28, 2024.


Authorized U.S. Representative

/s/ Sven (Bill) Ante Lundberg

Sven (Bill) Ante Lundberg

Exhibit 5.1



P.O. Box 7113

1007 JC Amsterdam

Beethovenstraat 400

1082 PR Amsterdam

T +31 20 71 71 000

F +31 20 71 71 111

     Amsterdam, February 28, 2024.



To the Company:


We have acted as legal counsel as to Dutch law to the Company in connection with the filing of the Registration Statement with the SEC. This opinion letter is rendered to you in order to be filed with the SEC as an exhibit to the Registration Statement.


Capitalised terms used in this opinion letter have the meanings set forth in Exhibit A to this opinion letter. The section headings used in this opinion letter are for convenience of reference only and are not to affect its construction or to be taken into consideration in its interpretation.


This opinion letter is strictly limited to the matters stated in it and may not be read as extending by implication to any matters not specifically referred to in it. Nothing in this opinion letter should be taken as expressing an opinion in respect of any representations or warranties, or other information, contained in any document reviewed by us in connection with this opinion letter.


In rendering the opinions expressed in this opinion letter, we have reviewed and relied upon a draft of the Registration Statement and pdf copies of the Corporate Documents and we have assumed that any issuance of Registered Shares shall be effected for bona fide commercial reasons. We have not investigated or verified any factual matter disclosed to us in the course of our review.


This opinion letter sets out our opinion on certain matters of the laws with general applicability of the Netherlands, and, insofar as they are directly applicable in the Netherlands, of the European Union, as at today’s date and as presently interpreted under published authoritative case law of the Dutch courts, the General Court and the Court of Justice of the European Union. We do not express any opinion on Dutch or European competition law, data protection law, tax law, securitisation law or regulatory law. No undertaking is assumed on our part to revise, update or amend this opinion letter in connection with, or to notify or inform you of, any developments and/or changes of Dutch law subsequent to today’s date. We do not purport to opine on the consequences of amendments to the Registration Statement or the Corporate Documents subsequent to the date of this opinion letter.


All legal relationships are subject to NautaDutilh N.V.’s general terms and conditions (see https://www.nautadutilh.com/terms), which apply mutatis mutandis to our relationship with third parties relying on statements of NautaDutilh N.V., include a limitation of liability clause, have been filed with the Rotterdam District Court and will be provided free of charge upon request. NautaDutilh N.V.; corporate seat Rotterdam; trade register no. 24338323.







The opinions expressed in this opinion letter are to be construed and interpreted in accordance with Dutch law. The competent courts at Amsterdam, the Netherlands, have exclusive jurisdiction to settle any issues of interpretation or liability arising out of or in connection with this opinion letter. Any legal relationship arising out of or in connection with this opinion letter (whether contractual or non-contractual), including the above submission to jurisdiction, is governed by Dutch law and shall be subject to the general terms and conditions of NautaDutilh. Any liability arising out of or in connection with this opinion letter shall be limited to the amount which is paid out under NautaDutilh’s insurance policy in the matter concerned. No person other than NautaDutilh may be held liable in connection with this opinion letter.


In this opinion letter, legal concepts are expressed in English terms. The Dutch legal concepts concerned may not be identical in meaning to the concepts described by the English terms as they exist under the law of other jurisdictions. In the event of a conflict or inconsistency, the relevant expression shall be deemed to refer only to the Dutch legal concepts described by the English terms.


For the purposes of this opinion letter, we have assumed that:


a.   each copy of a document conforms to the original, each original is authentic, and each signature is the genuine signature of the individual purported to have placed that signature;


b.  if any signature under any document is an electronic signature (as opposed to a handwritten (“wet ink”) signature) only, the method used for signing is sufficiently reliable;


c.   the Registration Statement has been or will be declared effective by the SEC in the form reviewed by us;


d.  at each Relevant Moment, (i) the Common Shares shall have been admitted for trading on a trading system outside the European Economic Area comparable to a regulated market or a multilateral trading facility as referred to in Section 2:86c(1) DCC and (ii) no financial instruments issued by the Company (or depository receipts for or otherwise representing such financial instruments) have been admitted to trading on a regulated market, multilateral trading facility or organised trading facility operating in the European Economic Area (and no request for admission of any such financial instruments to trading on any such trading venue has been made;


e.   each of the Deed of Incorporation and the Deed of Conversion is a valid notarial deed, and the Deed of Incorporation has been executed on the basis of a valid declaration of no objection (verklaring van geen bezwaar);


f.   the Current Articles are the Articles of Association currently in force and as they will be in force at each Relevant Moment;







g.  at each Relevant Moment, the authorised share capital (maatschappelijk kapitaal) of the Company shall allow for the issuance of the Registered Shares;


h.  at each Relevant Moment, the Company will not have (i) been dissolved (ontbonden), (ii) ceased to exist pursuant to a merger (fusie) or a division (splitsing), (iii) been converted (omgezet) into another legal form, either national or foreign, (iv) had its assets placed under administration (onder bewind gesteld), (v) been declared bankrupt (failliet verklaard), (vi) been granted a suspension of payments (surseance van betaling verleend), (vii) started or become subject to statutory proceedings for the restructuring of its debts (akkoordprocedure) or (viii) been made subject to similar proceedings in any jurisdiction or otherwise been limited in its power to dispose of its assets;


i.   any Registered Shares shall be issued, and any pre-emption rights in connection therewith shall have been excluded, pursuant to resolutions validly passed by the corporate body (orgaan) of the Company duly authorised to do so;


j.   the issue price for any Registered Shares shall at least equal the aggregate nominal value thereof, any such issue price shall have been satisfied in cash and shall have been received and accepted by the Company ultimately upon the issuance of the relevant Registered Shares and, where relevant, the Company shall have consented to payment in a currency other than Euro; and


k.  no Registered Shares shall be offered to the public (aanbieden aan het publiek) in the Netherlands other than in conformity with the Prospectus Regulation and the rules promulgated thereunder.


Based upon and subject to the foregoing and subject to the qualifications set forth in this opinion letter and to any matters, documents or events not disclosed to us, we express the following opinions:


Corporate Status


1.  The Company has been duly incorporated as a besloten vennootschap met beperkte aansprakelijkheid and is validly existing as a naamloze vennootschap.








Registered Shares


2.  Subject to receipt by the Company of payment in full for, or other satisfaction of the issue price for, the Registered Shares, and when issued by the Company and accepted by the acquiror(s) thereof, the Registered Shares shall be validly issued, fully paid and non-assessable.


The opinions expressed above are subject to the following qualifications:


A. Opinion 1 must not be read to imply that the Company cannot be dissolved (ontbonden). A company such as the Company may be dissolved, inter alia by the competent court at the request of the company’s board of directors, any interested party (belanghebbende) or the public prosecution office in certain circumstances, such as when there are certain defects in the incorporation of the company. Any such dissolution will not have retro-active effect.


B. Pursuant to Section 2:7 DCC, any transaction entered into by a legal entity may be nullified by the legal entity itself or its liquidator in bankruptcy proceedings (curator) if the objects of that entity were transgressed by the transaction and the other party to the transaction knew or should have known this without independent investigation (wist of zonder eigen onderzoek moest weten). The Dutch Supreme Court (Hoge Raad der Nederlanden) has ruled that in determining whether the objects of a legal entity are transgressed, not only the description of the objects in that legal entity’s articles of association (statuten) is decisive, but all (relevant) circumstances must be taken into account, in particular whether the interests of the legal entity were served by the transaction. Based on the objects clause contained in the Current Articles, we have no reason to believe that, by issuing Registered Shares, the Company would transgress the description of the objects contained in its Articles of Association. However, we cannot assess whether there are other relevant circumstances that must be taken into account, in particular whether the interests of the Company are served by issuing Registered Shares since this is a matter of fact.


C. Pursuant to Section 2:98c DCC, a company such as the Company may grant loans (leningen verstrekken) only in accordance with the restrictions set out in Section 2:98c DCC, and may not provide security (zekerheid stellen), give a price guarantee (koersgarantie geven) or otherwise bind itself, whether jointly and severally or otherwise with or for third parties (zich op andere wijze sterk maken of zich hoofdelijk of anderszins naast of voor anderen verbinden) with a view to (met het oog op) the subscription or acquisition by third parties of shares in its share capital or depository receipts. This prohibition also applies to its subsidiaries (dochtervennootschappen). It is generally assumed that a transaction entered into in violation of Section 2:98c DCC is null and void (nietig).








D. The opinions expressed in this opinion letter may be limited or affected by:


a.   rules relating to Insolvency Proceedings or similar proceedings under a foreign law and other rules affecting creditors’ rights generally;


b.  the provisions of fraudulent preference and fraudulent conveyance (Actio Pauliana) and similar rights available in other jurisdictions to insolvency practitioners and insolvency office holders in bankruptcy proceedings or creditors;


c.   claims based on tort (onrechtmatige daad);


d.  sanctions and measures, including but not limited to those concerning export control, pursuant to European Union regulations, under the Dutch Sanctions Act 1977 (Sanctiewet 1977) or other legislation;


e.   the Anti-Boycott Regulation, Anti Money Laundering Laws and related legislation;


f.   any intervention, recovery or resolution measure by any regulatory or other authority or governmental body in relation to financial enterprises or their affiliated entities; and


g.  the rules of force majeure (niet toerekenbare tekortkoming), reasonableness and fairness (redelijkheid en billijkheid), suspension (opschorting), dissolution (ontbinding), unforeseen circumstances (onvoorziene omstandigheden) and vitiated consent (i.e., duress (bedreiging), fraud (bedrog), abuse of circumstances (misbruik van omstandigheden) and error (dwaling)) or a difference of intention (wil) and declaration (verklaring).


E.  The term “non-assessable” has no equivalent in the Dutch language and for purposes of this opinion letter such term should be interpreted to mean that a holder of an Common Share shall not by reason of merely being such a holder be subject to assessment or calls by the Company or its creditors for further payment on such Common Share.








F.  This opinion letter does not purport to express any opinion or view on the operational rules and procedures of any clearing or settlement system or agency.


We consent to the filing of this opinion letter as an exhibit to the Registration Statement and also consent to the reference to NautaDutilh in the Registration Statement under the caption “Legal Matters”. In giving this consent we do not admit or imply that we are a person whose consent is required under Section 7 of the United States Securities Act of 1933, as amended, or any rules and regulations promulgated thereunder.


Sincerely yours,


/s/ NautaDutilh N.V.


NautaDutilh N.V.











  Anti Money Laundering Laws    The European Anti-Money Laundering Directives, as implemented in the Netherlands in the Money Laundering and Terrorist Financing Prevention Act (Wet ter voorkoming van witwassen en financieren van terrorisme) and the Dutch Criminal Code (Wetboek van Strafrecht).
  Anti-Boycott Regulation    The Council Regulation (EC) No 2271/96 of 22 November 1996 on protecting against the effects of the extra-territorial application of legislation adopted by a third country, and actions based thereon or resulting therefrom.
  Articles of Association    The Company’s articles of association (statuten) as they read from time to time.
  Bankruptcy Code    The Dutch Bankruptcy Code (Faillissementswet).
  Commercial Register    The Dutch Commercial Register (handelsregister).
  Common Shares    Common shares in the Company’s capital, with a nominal value of EUR 0.09 each.
  Company    Merus N.V., a public company with limited liability (naamloze vennootschap), registered with the Commercial Register under number 30189136.
  Corporate Documents    The Deed of Incorporation, the Deed of Conversion, the Deed of Amendment and the Current Articles.
  Current Articles    The Articles of Association as contained in the Deed of Amendment.
  DCC    The Dutch Civil Code (Burgerlijk Wetboek).
  Deed of Amendment    The deed of amendment to the Articles of Association of the Company dated May 28, 2021.
  Deed of Conversion    The deed of conversion and amendment to the Articles of Association dated May 19, 2016.






        Deed of Incorporation    The Company’s deed of incorporation (akte van oprichting) dated June 16, 2003.
  Insolvency Proceedings    Any insolvency proceedings within the meaning of Regulation (EU) 2015/848 on insolvency proceedings (recast), listed in Annex A thereto, and any statutory proceedings for the restructuring of debts (akkoordprocedure) pursuant to the Bankruptcy Code.
  NautaDutilh    NautaDutilh N.V.
  the Netherlands    The European territory of the Kingdom of the Netherlands and “Dutch” is in or from the Netherlands.
  Plan    The Merus N.V. 2016 Incentive Award Plan incorporated by reference as an exhibit to the Registration Statement.
  Prospectus Regulation    Regulation (EU) 2017/1129 on the prospectus to be published when securities are offered to the public or admitted to trading on a regulated market.
  Registered Shares    The number of Common Shares registered pursuant to the Registration Statement and available for issuance under the Plan.
  Registration Statement    The Company’s registration statement on Form S-8 filed or to be filed with the SEC in the form reviewed by us.
  Relevant Moment    Each time when one or more Registered Shares are issued by the Company.
  SEC    The United States Securities and Exchange Commission.

Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

The Board of Directors

Merus N.V.:

We consent to the use of our report dated February 28, 2024, with respect to the consolidated financial statements of Merus N.V., and the effectiveness of internal control over financial reporting, incorporated herein by reference.

/s/ KPMG Accountants N.V.

Amstelveen, The Netherlands

February 28, 2024


Exhibit 107.1

Calculation of Filing Fee Tables

Form S-8

(Form Type)

Merus N.V.

(Exact name of Registrant as Specified in Its Charter)

Table 1 - Newly Registered Securities





Price Per







   Amount of
Equity    Common shares, nominal value €0.09 per share    Rule 457(c) and Rule 457(h)    9,534,386(2)    $47.13(3)    $449,355,612     0.00014760     $66,325 
Total Offering Amounts       $449,355,612       $66,325
Total Fee Offsets             — 
Net Fee Due                   $66,325



In accordance with Rule 416 under the Securities Act of 1933, as amended, this registration statement shall be deemed to cover any additional securities that may from time to time be offered or issued under the Merus N.V. 2016 Incentive Award Plan, as amended (the “2016 Plan”) to prevent dilution resulting from stock splits, stock dividends or similar transactions. In addition, pursuant to Rule 416(c) under the Securities Act of 1933, as amended, this registration statement also covers an indeterminate amount of interests to be offered or sold pursuant to the employee benefit plan described herein.


Consists of 9,534,386 common shares of Merus N.V. (the “Registrant”) that may become issuable under the 2016 Plan pursuant to its terms.


Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act of 1933, as amended, and based upon the average of the high and low sale prices of the Registrant’s common shares as reported on the Nasdaq Global Market on February 23, 2024.

Table 2 - Fee Offset Claims and Sources




or Filer
























with Fee







with Fee



with Fee







Rule 457(p)